Financial Support
OPKO Connect provides comprehensive support
OPKO Connect offers support for your office on behalf of your patients who have been prescribed Rayaldee® (calcifediol).
Benefits Investigation
OPKO Connect will verify the patient’s insurance coverage for Rayaldee, including identifying
• | Prior authorization requirements |
• | Deductible, co-insurance, and out-of-pocket costs |
Prior Authorization (PA) Assistance

OPKO Connect will assist with any insurance-required PAs for Rayaldee by
• | Completing and submitting insurer-specific PA forms |
• | Confirming receipt of submission by insurance and facilitating a timely review |
• | Providing status from insurance to patients and their healthcare provider’s office |
Support for Appeals if the PA is Denied
OPKO Connect will
• | Confirm the reason for the PA denial and provide options for appeals submission |
• | Supply a letter of medical necessity (LMN) template specific to Rayaldee |
• | Provide appeal status from insurance to patients and their healthcare provider’s office |
Copay Assistance
Eligible, commercially insured patients can fill their Rayaldee prescription for $5 per month until the annual maximum limit is reached.

* | Eligible, commercially insured patients can fill their Rayaldee prescription for $5 per month. |
Patient Assistance Program (PAP)
For patients without Rayaldee pharmacy insurance coverage, OPKO Connect has a patient assistance program offering free medication. Eligibility criteria apply and annual reenrollment is required.
Download the application for patient assistance.
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* | Eligible, commercially insured patients can fill their Rayaldee prescription for $5 per month. |
To receive support for your patients, please complete a Rayaldee Service Request Form (SRF) and return to OPKO Connect.
• | Fax 1-844-660-7083 |
• | Email opkoconnect@rxallcare.com |
OPKO Connect services are available
by phone at 1-844-414-6756
or by email opkoconnect@rxallcare.com
Monday through Friday, 8am to 8pm ET
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Download the Rayaldee Service Request Form. |
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Download a letter of medical necessity. |
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Download an attestation letter for patients with vitamin D insufficiency. |