Find Support Right From the Start
OPKO Connect Can Help
Get the Support You Need. 1-844-414-OPKO (6756)
OPKO Connect, a program developed by the makers of Rayaldee® (calcifediol) extended-release capsules, offers comprehensive support. People who have been prescribed Rayaldee can speak with a pharmacist, get help with finding financial assistance for those who qualify, or receive support when talking with insurance companies.
OPKO Connect services are available Monday through Friday, 8 am to 8 pm ET by calling 1-844-414-OPKO (6756).
Affording Your Medicine
The makers of Rayaldee, OPKO Renal, are committed to making sure that every person who is eligible for Rayaldee and has a prescription, has access to treatment. With this commitment in mind, OPKO Connect was formed.
After you receive a prescription for Rayaldee, your healthcare provider can help you enroll in OPKO Connect for comprehensive support. The team at OPKO Connect is available to help identify people who may be eligible for copayment assistance, can assist with talking with insurance companies, and provide support in case of insurance issues or delays.
For help with your prescription for Rayaldee, call 1-844-414-OPKO (6756), option 2, to speak with a support specialist at OPKO Connect. Support specialists are available Monday through Friday from 8 am to 8 pm ET. Or download a form to get started.
Para obtener ayuda con su prescripción para Rayaldee, llame a 1-844-414-OPKO (6756) o descargue este formulario.
Frequently Asked Questions About Rayaldee and SHPT
Secondary hyperparathyroidism (SHPT) can develop as a complication of chronic kidney disease (CKD). SHPT occurs when the parathyroid makes too much of a type of hormone, called parathyroid hormone, or PTH.
People with stage 3 or 4 CKD are at risk for developing SHPT. It’s important for people with a diagnosis of SHPT and low vitamin D levels to receive effective treatment.
Left untreated, SHPT can cause health issues including osteoporosis, bone fractures, kidney stones, heart disease, and high blood pressure. Rayaldee has not been proven to completely get rid of vitamin D insufficiency nor control secondary hyperparathyroidism.
Rayaldee is a prescription oral medicine that is indicated for treating adults with secondary hyperparathyroidism with stage 3 or 4 chronic kidney disease and low vitamin D levels. Rayaldee helps to increase the levels of vitamin D and lowers the amount of parathyroid hormone found in the blood.
Your healthcare provider will keep track of how you are doing by monitoring certain levels in your blood. Vitamin D, parathyroid hormone, calcium, and phosphorus will be checked regularly. This will help your healthcare provider tell how well Rayaldee is working for you. Your dose of Rayaldee may be adjusted based on these results.
In clinical trials, Rayaldee has been well tolerated with about 5% of people withdrawing due to treatment-emergent effects (compared with around 4% of those on placebo).
The most common side effects (those occurring in more than 2% of people taking Rayaldee) were anemia (low levels of red blood cells or hemoglobin), infection in the nose or throat, increased blood creatinine (a lab test for measuring kidney function), difficulty breathing, cough, congestive heart failure, constipation, bronchitis, high potassium levels, and osteoarthritis.
Elevations in calcium, also known as hypercalcemia, may occur during treatment with Rayaldee. Six people in the clinical trial needed to have their dose of Rayaldee adjusted due to increases in calcium. A total of 4.2% of patients taking Rayaldee (vs 2.1% of patients taking placebo) in the clinical trials experienced at least one elevation in calcium above normal limits, and none of those were found to be clinically significant.
Secondary hyperparathyroidism (SHPT) is often accompanied by low levels of vitamin D and is characterized by high levels of parathyroid hormone (PTH). Over-the-counter vitamin D addresses only the low levels of vitamin D and not the high PTH and has not been FDA-approved for the treatment of SHPT. Ready to learn more about how Rayaldee works?
If you have questions about why you were prescribed Rayaldee, your health, or diagnosis, please speak with your healthcare provider.
If you have general questions about Rayaldee or secondary hyperparathyroidism, you can speak with a Rayaldee Clinical Pharmacist at OPKO Connect at 1-844-414-OPKO (6756), option 1.
If you have questions about OPKO Connect or want to talk about the financial support that may be available, call 1-844-414-OPKO (6756), option 2.
Specialty pharmacies are pharmacies with extra training to work with medications that help treat rare or chronic diseases. Most specialty pharmacies have pharmacists, nurses, and support staff with extensive training about the diseases in which they concentrate and the medicines they provide.
Specialty pharmacies can deliver your medicine to your home, help with insurance reimbursement, and talk directly with your healthcare team. Many prescribers of Rayaldee use specialty pharmacies to help provide support to their patients.
Many healthcare providers choose to utilize the support services available through OPKO Connect, which can be a hub to help talk with your insurance company and pharmacy. Many people receive their Rayaldee prescription through a specialty pharmacy that can deliver the medication directly to their door and provide additional support as needed.
OPKO Connect may be able to help you and your healthcare provider talk with your insurance company. Call 1-844-414-OPKO (6756), option 2, to learn more. Support specialists are available Monday through Friday, 8 am to 8 pm ET at 1-844-414-OPKO (6756).
Rayaldee is taken by mouth, once daily at bedtime. Your healthcare provider may adjust the dose based on results of your lab work.
Ready to learn more? Download the brochure for Rayaldee.